Home Antibody All anti-OTUB1 antibodies
Also for OTUB1 (NM_017670)
|Recombinant fragment corresponding to a region within amino acids 1 and 149 of OTUB1 (Uniprot ID#Q96FW1)|
|Human, Mouse (Predicted: Rat, Pig, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (100%), Pig (100%), Bovine (100%)
|Homo sapiens OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1|
|HSPC263; OTB1; OTU1|
Entrez Gene 55611 Human
Entrez Gene 107260 Mouse
Entrez Gene 293705 Rat
|The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate). A: Hela. B: Hep G2 . 12% SDS PAGE. TA307939 diluted at 1:1000.
Sample (50 ug of whole cell lysate). A: Mouse liver. 12% SDS PAGE. TA307939 diluted at 1:500.
Immunofluorescence analysis of methanol-fixed HeLa, using OTUB1(TA307939) antibody at 1:50 dilution.