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Home Antibody All anti-OTUB1 antibodies

Anti-OTUB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307939
  • Rabbit Polyclonal antibody to OTUB1 (OTU domain, ubiquitin aldehyde binding 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402607) , 20ug
100ul 325 3-7 Days
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WB(2)
IF(1)
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Also for OTUB1 (NM_017670)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 119 of Human OTUB1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.25mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1
Alternative NameHSPC263; OTB1; OTU1
Database LinkNP_060140
FunctionThe product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Related Pathway

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WB Image
A: Hela B: HepG2 (anti-OTUB1 antibody diluted at 1:1000)
WB Image
A: Mouse liver (anti-OTUB1 antibody diluted at 1:500)
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using OTUB1(anti-OTUB1 antibody) antibody at 1:50 dilution.

 

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