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Anti-OSM TrueMAB Antibody clone 2B6
TrueMAB Antibodies - Made against Authentic Protein Antigens
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|Recombinant protein expressed in E.coli corresponding to amino acids 25-252 of human OSM|
||0.5~1.0 mg/ml (Lot Dependent)
||WB 1:1000, IHC 1:50
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Puridied form mouse ascites fluids (Protein A or G Sepharose)
|Homo sapiens oncostatin M (OSM)|
|Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells|
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OSM (RC204277, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OSM.
Immunohistochemical staining of paraffin-embedded lung tissue using anti-OSMmouse monoclonal antibody. (TA500195, Dilution 1:50)