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Anti-ORP1 Antibody EPR8646


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against ORP1
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human ORP1 was used as an immunogen.
Clone NameEPR8646 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
Predicted MW Explanation 108 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens oxysterol binding protein-like 1A (OSBPL1A), transcript variant 1
Alternative NameORP-1; ORP1; OSBPL1B
Database LinkNP_060500
Entrez Gene 114876 Human
Entrez Gene 64291 Mouse
Entrez Gene 259221 Rat
FunctionORP1 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain (1). ORP1 binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Three ORP1 isoforms have been reported (isoform A: 50 kDa, isoform B: 108 kDa, isoform C: 106 kDa) (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-ORP1 antibody [EPR8646]; All lanes : Anti-ORP1 antibody [EPR8646] at 1/1000 dilution.Lane 1 : A549 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : U87-MG cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 108 kDa.Observed band size : 50-108 kDa .
Flow Cytometry - Anti-ORP1 antibody [EPR8646]; TA310737 at 1/10 dilution staining ORP1 in permeabilized A549 cells by Flow cytometry (red). Rabbit IgG negative control (green).


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