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Anti-OGG1 Antibody EPR4664(2)
Also for OGG1 (NM_002542)
|A synthetic peptide corresponding to residues at the C-terminus of human OGG1 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens 8-oxoguanine DNA glycosylase (OGG1), transcript variant 1a|
|HMMH; HOGG1; MUTM; OGH1|
Entrez Gene 4968 Human
|OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of OGG1 classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization (1). |
|Druggable Genome Base excision repair|
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Western blot - Anti-Ogg1 antibody [EPR4664(2)]; All lanes : Anti-Ogg1 antibody [EPR4664(2)] at 1/10000 dilution.Lane 1 : Human cerebellum lysate.Lane 2 : HeLa cell lysate.Lane 3 : JAR cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 39 kDa.
Other-Anti-Ogg1 antibody [EPR4664(2)](TA310735); Equilibrium disassociation constant (KD)..