Anti-OGG1 Antibody, EPR4664(2)

Also for OGG1 (NM_002542)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues at the C-terminus of human OGG1 was used as an immunogen.
Clone Name	EPR4664(2)	Isotype
Species Reactivity	Human	Concentration
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; IP: 1:10 - 100; FC: 1:10 - 100;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1a
Alternative Name	HMMH; HOGG1; MUTM; OGH1
Database Link	NP_002533
Function	OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of OGG1 classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization (1).
Related Pathway

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WB Image

Western blot analysis on (A) human cerebellum, (B) HeLa, (C) JAR, and (D) HepG2 cell lysates using anti-OGG1 RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

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FITC
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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-OGG1 Antibody EPR4664(2)

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data