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Anti-NTRK3 TRUEMAB Antibody clone 19B8
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for NTRK3 (NM_001007156)
|Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector|
|Human, Dog, Rat
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 3|
Entrez Gene 4916 Human
Entrez Gene 29613 Rat
Entrez Gene 100856261 Dog
|This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. |
|Protein KinaseTransmembraneDruggable Genome Neurotrophin signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NTRK3 (RC203781, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NTRK3.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-NTRK3 monoclonal antibody.