Home Antibody All anti-NR1H2 antibodies
Also for NR1H2 (NM_007121)
|LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), transcript variant 1|
|LXR-b; LXRB; NER; NER-I; RIP15; UNR|
|LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRa, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer’s disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the e3 allele.|
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of LXR-B in human lung tissue lysate with LXR-B antibody at (A) 1 and (B) 2 µg/ml.