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Home Antibody All anti-NQO1 antibodies

Anti-NQO1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308820
  • Rabbit polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, quinone 1)
100ul 325 3-7 Days
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WB(3)
IHC(1)
IF(1)
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Also for NQO1 (NM_001025434)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 213 and 274 of NQO1 (Uniprot ID#P15559)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Pig, Rhesus Monkey, Bovine, Guinea pig) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 31kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (92%), Rhesus Monkey (100%), Bovine (83%), Guinea pig (100%)

Reference Data

Target NameHomo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3
Alternative NameDHQU; DIA4; DTD; NMOR1; NMORI; QR1
Database LinkNP_001020605
Entrez Gene 1728 Human
Entrez Gene 705635 Monkey
FunctionThis gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . B: Raji. 12% SDS PAGE. TA308820 diluted at 1:1000.
WB Image
NQO1 antibody [C2C3], C-term detects NQO1 protein by Western blot analysis. A. 50 ug mouse heart lysate/extract. 12 % SDS-PAGE. NQO1 antibody [C2C3], C-term (TA308820) dilution: 1:500
WB Image
NQO1 antibody [C2C3], C-term detects NQO1 protein by Western blot analysis. A. 50 ug rat heart lysate/extract. 12 % SDS-PAGE. NQO1 antibody [C2C3], C-term (TA308820) dilution: 1:500
IHC Image
Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using NQO1(TA308820) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NQO1(TA308820) antibody at 1:200 dilution.

 

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