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Anti-NQO1 Antibody EPR3310
Also for NQO1 (NM_000903)
|A synthetic peptide corresponding to the C-terminus of human NQO1/Quinone 1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:2000; IP: 1:10
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 1|
|DHQU; DIA4; DTD; NMOR1; NMORI; QR1|
|NQO1/Quinoni 1 is a flavoenzyme that catalyzes two-electron reductive metabolism and detoxification of quinones and their derivatives leading to protection of cells against redox cycling and oxidative stress (1). NQO1/Quinoni 1 is mainly cytosolic, but its nuclear presence suggests its involvement in both chemoprevention and bioactivation of DNA-damaging antitumor agents (2). NQ01/Quinoni 1 may also play a role in the bioactivation of antitumor quinones such as mitomycin C (MMC), and has been proposed to have a protective effect against cancer caused by quinones and their metabolic precursors (3-4). |
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Western blot - NQO1 antibody [EPR3310]; All lanes : Anti-NQO1 antibody [EPR3310] at 1/2000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : A549 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 31 kDa.Observed band size : 31 kDa.