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Home Antibody All anti-NPTX2 antibodies

Anti-NPTX2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306565 Rabbit Polyclonal NPTX2 Antibody 100ug $325 2 Weeks
LC419275 NPTX2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for NPTX2 (NM_002523)
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OriGene Data

ImmunogenNPTX2 antibody was raised against a 16 amino acid peptide near the center of the human NPTX2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot Dependent
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 and 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens neuronal pentraxin II (NPTX2)
Alternative NameNARP; NP-II; NP2
Database LinkNP_002514
Entrez Gene 4885 Human
Entrez Gene 53324 Mouse
Entrez Gene 288475 Rat
FunctionNeuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and –dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson’s disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD. This NPTX2 antibody is predicted to be specific to NPTX2 and not recognize NPTX1.
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NPTX2 in mouse brain tissue lysate with NPTX2 antibody at (A) 0.5 and (B) 1 ug/ml.

IHC Image
Immunohistochemistry of NPTX2 in human brain with NPTX2 antibody at 5 ug/ml.

IF Image
Immunofluorescence of NPTX2 in Human Brain cells with NPTX2 antibody at 20 ug/mL.


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