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Anti-NPPB Antibody EPR3735
Also for NPPB (NM_002521)
|A synthetic peptide corresponding to residues in human BNP was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:2,000 - 20,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens natriuretic peptide B (NPPB)|
|B-type natriuretic peptide (BNP) is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload (1). The actions of BNP include natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is also found to help restore the body's salt and water balance and improve heart function (2). BNP is co-secreted along with a biologically inactive N-terminal fragment (NT-proBNP). Circulating BNP and NT-proBNP provide important information on cardiac dysfunction, hypervolemia, and risk in patients with severe impairment of kidney function (3). |
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Western blot - BNP antibody [EPR3735]; All lanes : Anti-BNP antibody [EPR3735] at 1/2000 dilution.Lane 1 : Human plasma.Lane 2 : Human fetal heart lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 15 kDa.Observed band size : 30 kDa .