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Home Antibody All anti-NPPB antibodies

Anti-NPPB Antibody EPR3735

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307437 Rabbit monoclonal antibody against BNP (clone EPR3735 ) 100ul $325 In Stock
LC400900 NPPB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BNP was used as an immunogen.
Clone NameEPR3735 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:2,000 - 20,000,
Predicted MW Explanation 15 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens natriuretic peptide B (NPPB)
Alternative NameBNP
Database LinkNP_002512
Entrez Gene 4879 Human
FunctionB-type natriuretic peptide (BNP) is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload (1). The actions of BNP include natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is also found to help restore the body's salt and water balance and improve heart function (2). BNP is co-secreted along with a biologically inactive N-terminal fragment (NT-proBNP). Circulating BNP and NT-proBNP provide important information on cardiac dysfunction, hypervolemia, and risk in patients with severe impairment of kidney function (3).
Related PathwaySecreted ProteinStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - BNP antibody [EPR3735]; All lanes : Anti-BNP antibody [EPR3735] at 1/2000 dilution.Lane 1 : Human plasma.Lane 2 : Human fetal heart lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 15 kDa.Observed band size : 30 kDa .
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