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Home Antibody All anti-NPPB antibodies

Anti-NPPB Antibody EPR3735

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307437
  • Rabbit monoclonal antibody against BNP (clone EPR3735 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400900) , 20ug
100ul 325 In Stock
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WB(1)
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Also for NPPB (NM_002521)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BNP was used as an immunogen.
Clone NameEPR3735 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:2,000 - 20,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens natriuretic peptide B (NPPB)
Alternative NameBNP
Database LinkNP_002512
FunctionB-type natriuretic peptide (BNP) is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload (1). The actions of BNP include natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is also found to help restore the body's salt and water balance and improve heart function (2). BNP is co-secreted along with a biologically inactive N-terminal fragment (NT-proBNP). Circulating BNP and NT-proBNP provide important information on cardiac dysfunction, hypervolemia, and risk in patients with severe impairment of kidney function (3).
Related Pathway

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WB Image
Western blot - BNP antibody [EPR3735]; All lanes : Anti-BNP antibody [EPR3735] at 1/2000 dilution.Lane 1 : Human plasma.Lane 2 : Human fetal heart lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 15 kDa.Observed band size : 30 kDa .

 

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