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Anti-NPM1 Antibody


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SKU Description Amount Price Availability*  
  • Rabbit Polyclonal Antibody against Nucleophosmin, mutant - AML Marker
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419282) , 20ug Explanation
100ul 325 In Stock
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Also for NPM1 (NM_002520)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to a C-terminal region of human mutant nucleophosmin (exact sequence is within residues 250-298).
Clone Name IsotypeIgG
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1: 1000, IHC: 1:50-1: 100, FC: 1: 100
Buffer100 mM glycine, 65 mM Tris, pH 7.0 in 50% glycerol
Purification Affinity purified

Reference Data

Target NameHomo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1
Alternative NameB23; NPM
Database LinkNP_002511
Entrez Gene 4869 Human
FunctionNucleophosmin (NPM) is a multi-functional protein that is involved in many cellular activities including cell growth, proliferation and transformation. It is frequently overexpressed in solid tumors, and has recently been found to be mutated and aberrantly localized in the cytoplasm of leukaemic blasts in patients with acute myeloid leukemia (AML).
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Detection of mutant nucleophosmin in OCI-AML3 lysates
IF Image
NPM1 localization by immunofluorescence in OCI-AML3 cells


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