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Home Antibody All anti-NOX4 antibodies

Anti-NOX4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323912
  • Anti-NOX4 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 210-424 amino acids of human NADPH oxidase 4
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens NADPH oxidase 4 (NOX4), transcript variant 1
Alternative NameKOX; KOX-1; RENOX
Database LinkNP_058627
FunctionThis gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction; cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Related Pathway

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IHC Image
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human gastric cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NOX4 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200)

 

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