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Home Antibody All anti-NOX4 antibodies

Anti-NOX4 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA323911 Anti-NOX4 Rabbit Polyclonal Antibody 100ul 325
2-3 Weeks
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OriGene Data

ImmunogenFusion protein corresponding to a region derived from 210-424 amino acids of human NADPH oxidase 4
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:25-100
Predicted MW Explanation 67kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens NADPH oxidase 4 (NOX4), transcript variant NOX4B
Alternative NameKOX; KOX-1; RENOX
Database LinkNP_001137308
Entrez Gene 50507 Human
Entrez Gene 50490 Mouse
Entrez Gene 85431 Rat
FunctionThis gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction; cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 67 kDa . Positive control: Human kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

IHC Image
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using NOX4 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification: x200)


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