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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-NME2 antibodies

Anti-NME2 Antibody EPR8351

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA311008
  • Rabbit Monoclonal antibody against Nm23-H2 (NME2)
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(1)
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Also for NME2 (NM_001018137)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
Gene NameHomo sapiens NME/NM23 nucleoside diphosphate kinase 2 (NME2), transcript variant 2
Synonyms:NDKB; NDPK-B; NDPKB; NM23-H2; NM23B; PUF
ImmunogenA synthetic peptide corresponding to residues in human Nm23-H2 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR8351 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000 - 10,000;
BackgroundNucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (NME1) and 'B' (Nm23-H2) isoforms (1). Nm23-H2 plays a major role in the synthesis of nucleoside triphosphates other than ATP. It negatively regulates Rho activity by interacting with AKAP13/LBC. Nm23-H2 acts as a transcriptional activator of MYC, binds DNA non-specifically, and exhibits histidine protein kinase activity (2).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) LnCaP, (B) PC-12, (C) CHO, (D) 293T, (E) human spleen, and (F) human thyroid lysates using anti-Nm23-H2 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Nm23-H2 RabMAb.

 

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