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Anti-NME2 Antibody EPR8351


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against Nm23-H2 (NME2)
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Nm23-H2 was used as an immunogen.
Clone NameEPR8351 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
Predicted MW Explanation 17 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens NME/NM23 nucleoside diphosphate kinase 2 (NME2), transcript variant 2
Alternative NameNDKB; NDPK-B; NDPKB; NM23-H2; NM23B; PUF
Database LinkNP_001018147
Entrez Gene 4831 Human
Entrez Gene 18103 Mouse
Entrez Gene 83782 Rat
FunctionNucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (NME1) and 'B' (Nm23-H2) isoforms (1). Nm23-H2 plays a major role in the synthesis of nucleoside triphosphates other than ATP. It negatively regulates Rho activity by interacting with AKAP13/LBC. Nm23-H2 acts as a transcriptional activator of MYC, binds DNA non-specifically, and exhibits histidine protein kinase activity (2).
Related PathwayTranscription FactorsDruggable Genome Purine metabolismPyrimidine metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-NME2 antibody [EPR8351]; All lanes : Anti-NME2 antibody [EPR8351] at 1/1000 dilution.Lane 1 : LnCaP cell lysate.Lane 2 : PC-12 cell lysate.Lane 3 : CHO cell lysate.Lane 4 : 293T cell lysate.Lane 5 : Human spleen lysate.Lane 6 : Human thyroid lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 17 kDa.
Other-Anti-NME2 antibody [EPR8351](TA311008); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NME2 antibody [EPR8351]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling NME2 with TA311008 at 1/100 dilution.


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