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Home Antibody All anti-NLRP6 antibodies

Anti-NLRP6 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320131
  • Rabbit Polyclonal NALP6 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenNALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, IF: 20 ug/ml
BufferNALP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NALP6 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 1
Alternative NameAVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5
Database LinkNP_612202
Entrez Gene 171389 Human
FunctionNALP6 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-κB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NALP6 in human heart tissue lysate with NALP6 antibody at 1 ?g/ml in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunofluorescence of NALP6 in human brain tissue with NALP6 antibody at 20 ug/mL.

 

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