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TTF1 UltraMAB Antibody, Clone UMAB162

UltraMAB™ Antibodies - Validated with 10K Protein Chip


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SKU Description Datasheet Price Availability*  
  • TTF1 (NKX2-1) mouse monoclonal antibody,clone UMAB162, 100 ul
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  • TTF1 (NKX2-1) mouse monoclonal antibody,clone UMAB162, 30 ul
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OriGene Data

ImmunogenFull length human recombinant protein of human NKX2-1 ( NP_003308) produced in E.coli.
Clone NameClone UMAB162 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC Suggested Dilutions IHC 1:200,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 2
Alternative NameBCH; BHC; NK-2; NKX2.1; NKX2A; TEBP; TITF1; TTF-1; TTF1
Database LinkNP_003308
FunctionThis gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb
Related Pathway

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Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-NKX2-1 Mouse monoclonal antibody. (UM800057, heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)


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