Home Antibody All anti-NKX2-2 antibodies
Anti-NKX2-2 Antibody Polyclonal
Also for NKX2-2 (NM_002509)
|NKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|NKX2-2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NKX2-2 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens NK2 homeobox 2 (NKX2-2)|
|NKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α-, β- and PP cells, and in NKX2-2-null mice embryos, all β-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance. |
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Western blot analysis of NKX2-2 in rat kidney tissue lysate with NKX2-2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of NKX2-2 in human kidney tissue with NKX2-2 antibody at 2.5 ug/mL.