Home Antibody All anti-NIPSNAP1 antibodies
Also for NIPSNAP1 (NM_003634)
|NIPSNAP antibody was raised against a 19 amino acid peptide from near the center of human NIPSNAP.|
|Human, Mouse, Rat
||WB: 0.5 - 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens nipsnap homolog 1 (C. elegans) (NIPSNAP1), transcript variant 1|
|NIPSNAP, C. elegans|
Entrez Gene 8508 Human
Entrez Gene 18082 Mouse
Entrez Gene 360971 Rat
|NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.|
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Western blot analysis of NIPSNAP in human brain tissue lysate with NIPSNAP antibody at (A) 0.5 and (B) 1 ug/ml.
Immunohistochemical staining of human brain tissue using Nipsnap antibody at 2.5 ug/ml.