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Anti-NFKBIB Antibody EPR5037
Also for NFKBIB (NM_001001716)
|A synthetic peptide corresponding to residues on the C-terminus in human IKappaB-beta was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt.
|Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2|
|NFkB1 or NFkB2 is bound to REL, RELA, or RELB to form the NFkB complex. The NFkB complex is inhibited by IKappaB proteins, which inactivate NFkappaB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKappaB proteins by kinases (IKappaB-alpha or IKappaB-beta) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex (1).|
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Western blot - IKB beta antibody [EPR5037]; All lanes : Anti-IKB beta antibody [EPR5037] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : THP-1 cell lysate.Lane 4 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 37 kDa.Observed band size : 48 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IKB beta antibody [EPR5037]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue using TA311003 at a dilution of 1/100.