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Home Antibody All anti-NFKBIB antibodies

Anti-NFKBIB Antibody EPR5037

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311003
  • Rabbit Monoclonal antibody against IKappaB-beta (NFKBIB)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424220) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for NFKBIB (NM_001001716)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human IKappaB-beta was used as an immunogen.
Clone NameEPR5037 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2
Alternative NameIKBB; TRIP9
Database LinkNP_001001716
Entrez Gene 4793 Human
FunctionNFkB1 or NFkB2 is bound to REL, RELA, or RELB to form the NFkB complex. The NFkB complex is inhibited by IKappaB proteins, which inactivate NFkappaB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKappaB proteins by kinases (IKappaB-alpha or IKappaB-beta) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex (1).
Related PathwayStem cell - PluripotencyTranscription Factors Chemokine signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayCytosolic DNA-sensing pathwayT cell receptor signaling pathwayB cell receptor signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IKB beta antibody [EPR5037]; All lanes : Anti-IKB beta antibody [EPR5037] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : THP-1 cell lysate.Lane 4 : MCF7 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 37 kDa.Observed band size : 48 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IKB beta antibody [EPR5037]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue using TA311003 at a dilution of 1/100.

 

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