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Anti-NFKBIB Antibody EPR5037
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for NFKBIB (NM_001001716)
|A synthetic peptide corresponding to residues on the C-terminus in human IKappaB-beta was used as an immunogen.|
||WB: 1:10,000 - 50,000; IHC 1:250 - 500;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2|
|NFkB1 or NFkB2 is bound to REL, RELA, or RELB to form the NFkB complex. The NFkB complex is inhibited by IKappaB proteins, which inactivate NFkappaB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKappaB proteins by kinases (IKappaB-alpha or IKappaB-beta) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex (1).|
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Western blot analysis on (A) Jurkat, (B) HeLa, (C) THP-1, and (D) MCF-7 cell lysates using anti-IKappaB-beta RabMAb.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IkappaB-beta RabMAB.