Home Antibody All anti-NEIL3 antibodies
Also for NEIL3 (NM_018248)
|The antiserum was produced against synthesized peptide derived from internal of human NEIL3.|
|Human (Identities = 100%, Positives = 100%);Mouse (Identities = 100%, Positives = 100%)
||WB: 1:500~1:3000 ELISA: 1:40000
|Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
|NEIL3 antibody detects endogenous levels of total NEIL3 protein.
|Homo sapiens nei endonuclease VIII-like 3 (E. coli) (NEIL3)|
|FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3|
Entrez Gene 55247 Human
Entrez Gene 234258 Mouse
|NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008].|
|Druggable Genome Base excision repair|
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Western blot analysis of extracts from COLO cells, HUVEC cells, HepG2 cells and HeLa cells, using NEIL3 antibody.The lane on the right is treated with the synthesized peptide.