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Home Antibody All anti-NEFM antibodies

Anti-NEFM Antibody EP675Y

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303831 Rabbit monoclonal antibody against Neurofilament-L (C-Term)(EP675Y) 100ul $325 In Stock
LC417338 NEFM HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-term of human NF-L was used as immunogen.
Clone NameEP675Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50,000; FC: 1:70; IP: 1:50
Predicted MW Explanation 61 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens neurofilament, medium polypeptide (NEFM), transcript variant 1
Alternative NameNEF3; NF-M; NFM
Database LinkNP_005373
Entrez Gene 4741 Human
Entrez Gene 18040 Mouse
Entrez Gene 24588 Rat
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Related Pathway Amyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - 68kDa Neurofilament antibody [EP675Y] - Carboxyterminal end; Anti-68kDa Neurofilament antibody [EP675Y] at 1/50000 dilution + SH-SY5Y cell lysate at 10 ug.Secondary.goat anti-rabbit HRP labelled at 1/2000 dilution.Predicted band size : 61 kDa.Observed band size : 68 kDa .
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