Home Antibody All anti-NDUFS4 antibodies
Also for NDUFS4 (NM_002495)
|Recombinant fragment corresponding to a region within amino acids 1 and 175 of NDUFS4 (Uniprot ID#O43181)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) (NDUFS4)|
Entrez Gene 4724 Human
Entrez Gene 17993 Mouse
|This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq]|
|Druggable Genome Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's disease|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308443 diluted at 1:1000.
NDUFS4 antibody detects NDUFS4 protein by Western blot analysis. A. 50 ug Rat heart lysate/extract. 12% SDS-PAGE. NDUFS4 antibody (TA308443) dilution: 1:1000.
Sample(30ug whole cell lysate). A: 293T. 12% SDS PAGE. TA308443 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded OVCA, using NDUFS4(TA308443) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using NDUFS4(TA308443) antibody at 1:100 dilution.