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Home Antibody All anti-NDUFS1 antibodies

Anti-NDUFS1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308300 Rabbit Polyclonal antibody to NDUFS1 (NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)) 100ul $325 3-7 Days
LC417579 NDUFS1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(3)
IHC(1)
IF(1)
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Also for NDUFS1 (NM_005006)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 432 and 664 of NDUFS1 (Uniprot ID#P28331)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Chimpanzee) Concentration0.84mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 28kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (NDUFS1), transcript variant 1
Alternative NameCI-75k; CI-75Kd; PRO1304
Database LinkNP_004997
Entrez Gene 4719 Human
Entrez Gene 227197 Mouse
FunctionThe protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. [provided by RefSeq]
Related Pathway Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308300 diluted at 1:1000.
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Sample (50 ug of whole cell lysate) .   A: Rat brain.   12% SDS PAGE .   TA308300 diluted at 1:1000.    
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Sample (30 ug of whole cell lysate). A: Molt-4 . 12% SDS PAGE. TA308300 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded Colon ca, using NDUFS1(TA308300) antibody at 1:250 dilution.
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Immunofluorescence analysis of methanol-fixed A431, using NDUFS1(TA308300) antibody at 1:200 dilution.
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