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Anti-NCOA3 Antibody EPR4374(3)

WB(1)

IHC(1)

Gene Name Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 3 Synonyms: ACTR; AIB-1; AIB1; bHLHe42; CAGH16; CTG26; KAT13B; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1 Immunogen A synthetic peptide corresponding to residues on the C-terminus in human SRC-3 was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR4374(3) Isotype Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC Suggested Dilutions WB: 1:1,000 - 10,000; Background SRC-3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. It has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. SRC-3 is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. In addition, a polymorphic repeat region is found in the C-terminus of the protein (1). Related Pathway

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • NCOA3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • NCOA3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Ncoa3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • NCOA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Ncoa3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 3 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 3 as transfection-ready DNA Related cDNA Clones • Homo sapiens nuclear receptor coactivator 3 (NCOA3) transcript variant 3 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)