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Anti-NCF2 Antibody EPR5064
Also for NCF2 (NM_000433)
|A synthetic peptide corresponding to residues in human p67phox / NCF2 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||ICC: 1:500 - 1:1000; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:500 - 1:1000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens neutrophil cytosolic factor 2 (NCF2), transcript variant 1|
|NCF-2; NOXA2; P67-PHOX; P67PHOX|
|p67phox is known as neutrophil cytosolic factor 2 (NCF2), the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide, which is delivered to the lumen of the neutrophil phagosome. Mutations in p67phox / NCF2, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.|
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Western blot - NOXA2/p67phox antibody [EPR5064]; All lanes : Anti-NOXA2/p67phox antibody [EPR5064] at 1/1000 dilution.Lane 1 : HL-60 cells treated with dexomethasome, dimethyl sulfoxide, and TPA.Lane 2 : THP-1 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 60 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NOXA2/p67phox antibody [EPR5064]; Immunohistochemical analysis of NOXA2/p67phox in paraffin-embedded Human spleen tissue using TA307847 at 1/500 dilution