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Home Antibody All anti-NCAM1 (CD56) antibodies

Anti-NCAM1 (CD56) Antibody EPR2566


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SKU Description Amount Price Availability*  
TA306984 Rabbit monoclonal antibody against CD56/NCAM (clone EPR2566 ) 100ul $325 In Stock
LC405745 NCAM1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for NCAM1 (CD56) (NM_181351)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in extracellular domain of human CD56/NCAM was used as an immunogen.
Clone NameEPR2566 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens neural cell adhesion molecule 1 (NCAM1), transcript variant 2
Alternative NameCD56; MSK39; NCAM
Database LinkNP_851996
Entrez Gene 4684 Human
FunctionThe neural cell adhesion molecule (NCAM/CD56) is a homophilic binding glycoprotein belonging to immunoglobulin (Ig) superfamily. It is commonly found on the surface of neurons, NK cells, gilas, and neuroendocrine tissues, and it is involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM mediates axon growth, fasciculation, and cell adhesion by homophilic and heterophilic interactions (1). Due to alternative splicing, at least 27 different isoforms of NCAM mRNAs has been identified, leading to variety of NCAM isoforms (2). Three major NCAM isoforms are: 140 and 180 kDa transmembrane forms (NCAM-140, NCAM-180), and 120 kDa glycophosphatidylinositol (GPI)-linked isoform (NCAM120) (3).
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Prion diseases

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-NCAM antibody [EPR2566]; All lanes : Anti-NCAM antibody [EPR2566] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : Human fetal brain cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 95 kDa.Observed band size : 140-180 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NCAM antibody [EPR2566]; Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human glioma tissue staining NCAM with TA306984 at 1/100 dilution.


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