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Home Antibody All anti-NBN antibodies

Anti-NBN TRUEMAB Antibody Clone1G8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA801552
  • NBN mouse monoclonal antibody,clone 1G8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419300) , 20ug Explanation
100ul 325 In Stock
CF801552
  • Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody,clone 1G8
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 183-460 of human NBN (NP_002476)produced in E.coli.
Clone NameClone1G8 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 84.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens nibrin (NBN)
Alternative NameAT-V1; AT-V2; ATV; NBS; NBS1; P95
Database LinkNP_002476
Entrez Gene 4683 Human
FunctionMutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Homologous recombination

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NBN (RC214682, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NBN.

 

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