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Anti-N4BP1 Antibody Polyclonal
Also for N4BP1 (NM_153029)
|N4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|N4BP1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|N4BP1 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens NEDD4 binding protein 1 (N4BP1)|
|FLJ31821; KIAA0615; MGC176730|
|N4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.|
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Western blot analysis of N4BP1 in HeLa cell lysate with N4BP1 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of N4BP1 in HeLa cells with N4BP1 antibody at 10 ug/mL.