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Home Antibody All anti-Mbd2 antibodies

Anti-Mbd2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA318881 Rabbit polyclonal anti-MBD2a antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 164 of rat MBD2a
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit anti- MBD2a polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1
Alternative NameDMTase; NY-CO-41
Database LinkNP_003918
Entrez Gene 8932 Human
Entrez Gene 17191 Mouse
Entrez Gene 680172 Rat
FunctionThe MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein, whereas MBD2b lacks the 152 amino acids N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression.
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of MBD2a using Jurkat cell lysate.


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