Home Antibody All anti-MYT1L antibodies
Also for MYT1L (NM_015025)
|Rabbit polyclonal MYT1L antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MYT1L.|
|Human, Mouse, Rat
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens myelin transcription factor 1-like (MYT1L), transcript variant 2|
Entrez Gene 23040 Human
Entrez Gene 17933 Mouse
Entrez Gene 116668 Rat
|The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.|
|Transcription Factors |
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Western blot analysis of MYT1L in mouse brain tissue lysate with MYT1L antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.