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Anti-MYD88 TRUEMAB Antibody clone 1B4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for MYD88 (NM_002468)
|Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.|
|WB, IF, FC
||WB 1:2000, IF 1:100, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens myeloid differentiation primary response 88 (MYD88), transcript variant 2|
|This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]. |
Toll-like receptor signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYD88 (RC229151, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYD88.
Anti-MYD88 mouse monoclonal antibody (TA502104) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYD88(RC202253).
HEK293T cells transfected with either RC202253 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MYD88 antibody(TA502104), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-MYD88 antibody(TA502104),(Red), compared to a nonspecific negative control antibody,(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-MYD88 antibody(TA502104),(Red), compared to a nonspecific negative control antibody,(Blue).