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Anti-MYC TRUEMAB Antibody Clone 5E9G2
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Full length human recombinant protein of human Myc (NP_002458) produced in 293T|
|Human , Dog , Rat , Monkey
|| WB 1:200~4000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)|
|bHLHe39; c-Myc; MRTL; MYCC|
|The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]. |
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYC (RC201611, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYC.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MYC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Anti-MYC mouse monoclonal antibody (TA507203) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYC(RC201611).
Immunofluorescent staining of HeLa cells using anti-MYC mouse monoclonal antibody (TA507203).