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Home Antibody All anti-MYB antibodies

Anti-MYB Antibody EP769Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300706
  • Rabbit Monoclonal Antibody against MYB (Clone EP769Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401654) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human c-myb was used as an immunogen.
Clone NameEP769Y IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:100 - 1:250; IP: 1:50; ChIP: Use at an assay dependent dilution
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens v-myb avian myeloblastosis viral oncogene homolog (MYB), transcript variant 2
Alternative Namec-myb; c-myb_CDS; Cmyb; efg
Database LinkNP_005366
FunctionThe c-Myb proto-oncogene is a 75 kDa protein involved in growth regulation and differentiation in many different cell types but it is predominantly expressed in immature hemopoietic cells where it plays an important role in cell proliferation. c-Myb activity is directly regulated by cyclin D1 and CDKs and it is believed that c-Myb activity is regulated during the cell cycle in hematopoietic cells (2). Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth (3). c-Myb binds to promoter sequences of genes such as c-Myc or Bcl-2 that are expressed in cutaneous T-cell lymphoma.
Related Pathway
Wnt Signaling Pathway

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WB Image
Western blot - v-Myb / c-Myb antibody [EP769Y]; Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade at 1/10000 dilution + Ramos membrane.Predicted band size : 72 kDa.Observed band size : 72,75 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - v-Myb / c-Myb antibody [EP769Y]; Ab45150 staining human v-Myb / c-Myb in human cervical carcinoma by immunohistochemistry using paraffin embedded tissue.

 

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