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Anti-MYB Antibody EP769Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300706 Rabbit Monoclonal Anti-v-Myb + c-Myb (phospho S11) Antibody [EP769Y] - ChIP Grade 100ul $325 In Stock
LC401654 MYB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human c-myb was used as an immunogen.
Clone NameEP769Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:100 - 1:250; IP: 1:50; ChIP: Use at an assay dependent dilution
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens v-myb avian myeloblastosis viral oncogene homolog (MYB), transcript variant 2
Alternative Namec-myb; c-myb_CDS; Cmyb; efg
Database LinkNP_005366
Entrez Gene 4602 Human
FunctionThe c-Myb proto-oncogene is a 75 kDa protein involved in growth regulation and differentiation in many different cell types but it is predominantly expressed in immature hemopoietic cells where it plays an important role in cell proliferation. c-Myb activity is directly regulated by cyclin D1 and CDKs and it is believed that c-Myb activity is regulated during the cell cycle in hematopoietic cells (2). Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth (3). c-Myb binds to promoter sequences of genes such as c-Myc or Bcl-2 that are expressed in cutaneous T-cell lymphoma.
Related PathwayES Cell Differentiation/IPSStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - v-Myb / c-Myb antibody [EP769Y]; Anti-v-Myb + c-Myb antibody [EP769Y] - ChIP Grade at 1/10000 dilution + Ramos membrane.Predicted band size : 72 kDa.Observed band size : 72,75 kDa .

IHC Image
Immunohistochemistry (Paraffin-embedded sections) - v-Myb / c-Myb antibody [EP769Y]; Ab45150 staining human v-Myb / c-Myb in human cervical carcinoma by immunohistochemistry using paraffin embedded tissue.


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