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Home Antibody All anti-MVP antibodies

Anti-MVP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308784
  • Rabbit Polyclonal antibody to MVP/LRP (major vault protein)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417505) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for MVP (NM_005115)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 158 and 350 of LRP(MVP)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens major vault protein (MVP), transcript variant 2
Alternative NameLRP; VAULT1
Database LinkNP_005106
FunctionThis gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]
Related Pathway

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WB Image
A: Molt-4 (anti-MVP antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(anti-MVP antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(anti-MVP antibody) antibody at 1:200 dilution.

 

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