Home Antibody All anti-MVP antibodies
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 158 and 350 of LRP(MVP)|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens major vault protein (MVP), transcript variant 2|
|This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]|
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A: Molt-4 (anti-MVP antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(anti-MVP antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(anti-MVP antibody) antibody at 1:200 dilution.