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Home Antibody All anti-MVK antibodies

Anti-MVK Antibody EPR6507

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310705
  • Rabbit Monoclonal antibody against MVK
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424723) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for MVK (NM_000431)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MVK was used as an immunogen.
Clone NameEPR6507 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC/IF or IHC-P.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens mevalonate kinase (MVK), transcript variant 1
Alternative NameLRBP; MK; MVLK; POROK3
Database LinkNP_000422
FunctionMVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized by psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in MVK also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MVK antibody [EPR6507]; All lanes : Anti-MVK antibody [EPR6507] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Caco-2 cell lysate.Lane 4 : Human fetal liver lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 42 kDa.Observed band size : 42 kDa.
Assay Image
Other-Anti-MVK antibody [EPR6507](TA310705); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-MVK antibody [EPR6507]; TA310705, at a 1/10 dilution, positively staining MVK in permeabilized HepG2 cells (red). A Rabbit IgG was used as negative control (green).

 

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