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Home Antibody All anti-MVK antibodies

Anti-MVK Antibody EPR6507

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310705
  • Rabbit Monoclonal antibody against MVK
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424723) , 20ug
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for MVK (NM_000431)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MVK was used as an immunogen.
Clone NameEPR6507 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC/IF or IHC-P.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens mevalonate kinase (MVK), transcript variant 1
Alternative NameLRBP; MK; MVLK; POROK3
Database LinkNP_000422
FunctionMVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized by psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in MVK also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MVK antibody [EPR6507]; All lanes : Anti-MVK antibody [EPR6507] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Caco-2 cell lysate.Lane 4 : Human fetal liver lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 42 kDa.Observed band size : 42 kDa.
Assay Image
Other-Anti-MVK antibody [EPR6507](TA310705); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-MVK antibody [EPR6507]; TA310705, at a 1/10 dilution, positively staining MVK in permeabilized HepG2 cells (red). A Rabbit IgG was used as negative control (green).

 

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