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Home Antibody All anti-MUTYH antibodies

Anti-MUTYH Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302935
  • Goat Polyclonal Antibody against MUTYH
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence according to NP_036354.1; NP_001041636.1; NP_001041637.1; NP_001041638.1; NP_001041639.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens mutY homolog (MUTYH), transcript variant alpha3
Alternative NameMYH
Database LinkNP_001041636
Entrez Gene 4595 Human
FunctionThis gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayStem cell - PluripotencyDruggable Genome Base excision repair

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302935 (0.1µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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