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Anti-MTRR Antibody EPR8349
Also for MTRR (NM_002454)
|A synthetic peptide corresponding to residues on the C-terminus in human MTRR was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IF
||WB: 1:10000 - 1:50000; ICC/IF: 1:100 - 1:250
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1|
Entrez Gene 4552 Human
|Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. MTRR regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase (1).|
|Druggable Genome |
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Western blot - Anti-MTRR antibody [EPR8349]; All lanes : Anti-MTRR antibody [EPR8349] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 80 kDa.
Other-Anti-MTRR antibody [EPR8349](TA310700); Equilibrium disassociation constant (KD)..
Immunocytochemistry/ Immunofluorescence - Anti-MTRR antibody [EPR8349]; TA310700 at 1/100 dilution staining MTRR in HeLa cells by immunofluorescence.