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Home Antibody All anti-MTRR antibodies

Anti-MTRR Antibody EPR8349

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310700
  • Rabbit Monoclonal antibody against MTRR
100ul $325 3-7 Days
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WB(1)
IF(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human MTRR was used as an immunogen.
Clone NameEPR8349 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:10000 - 1:50000; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1
Alternative NamecblE; MSR
Database LinkNP_002445
FunctionMethionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. MTRR regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase (1).
Related Pathway

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WB Image
Western blot - Anti-MTRR antibody [EPR8349]; All lanes : Anti-MTRR antibody [EPR8349] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 80 kDa.
Assay Image
Other-Anti-MTRR antibody [EPR8349](TA310700); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-MTRR antibody [EPR8349]; TA310700 at 1/100 dilution staining MTRR in HeLa cells by immunofluorescence.

 

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