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Anti-MTDH Antibody EP4445
Also for MTDH (NM_178812)
|A synthetic peptide corresponding to residues in human Metadherin was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens metadherin (MTDH)|
|3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3|
Entrez Gene 92140 Human
Entrez Gene 67154 Mouse
Entrez Gene 170910 Rat
|Metadherin is a potentially crucial mediator of tumor malignancy and a key factor of oncogenic signaling pathways (1). Elevated levels have been observed in some human tumor types, such as breast cancer, prostate cancer, hepatocellular carcinoma, neuroblastoma, esophageal squamous cell carcinoma (ESCC) and non-small cell lung cancer (NSCLC) (2). Metadherin promotes anchorage-independent growth of immortalized melanocytes and astrocytes, which is a key component in tumor cell expansion (3). Several signaling pathways have been found to be associated with the expression of Metadherin, including Ha-ras, PI3K/Akt, NF-?B and Wnt/ß-catenin. (2).|
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Western blot - Anti-LYRIC antibody [EP4445]; All lanes : Anti-LYRIC antibody [EP4445] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : PC3 cell lysate.Lane 4 : PC12 cell lysate.Lane 5 : NIH 3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 64 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in paraffin-embedded Human brain tissues by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in paraffin-embedded Human breast tissues by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - Anti-LYRIC antibody [EP4445]; TA310986 at 1/100 dilution staining LYRIC in HeLa cells by Immunofluorescence.