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Home Antibody All anti-MMP17 antibodies

Anti-MMP17 Antibody EP1270Y

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SKU Description Amount Price Availability*  
TA303604 Rabbit monoclonal antibody against MMP-17 (EP1270Y ) 100ul $325 In Stock
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WB(1)
IHC(2)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on human MMP-17 was used as an immunogen.
Clone NameEP1270Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:50 - 1:100; IHC-FoFr: Use at an assay dependent concentration
Predicted MW Explanation 67 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens matrix metallopeptidase 17 (membrane-inserted) (MMP17)
Alternative NameMT4-MMP
Database LinkNP_057239
Entrez Gene 4326 Human
Entrez Gene 23948 Mouse
Entrez Gene 288626 Rat
FunctionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - MMP17 antibody [EP1270Y]; Anti-MMP17 antibody [EP1270Y] at 1/1000 dilution + Mouse brain lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 67 kDa.Observed band size : 58 kDa .
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Immunohistochemistry (Paraffin-embedded sections) - MMP17 antibody [EP1270Y]; Ab51075 (1:50) staining human MMP17 in human lymphoma tissue by immunohistochemistry using paraffin embedded tissue.
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-MMP17 antibody [EP1270Y]; Immunohistochemical analysis of rat basolateral amygdala tissue, staining MMP17 with TA303604. Tissue was permeabilized with 0.5% Triton-X 100 before incubating with primary antibody (1/100) for 48 hours at 4°C. An AlexaFluor?568 goat anti-rabbit IgG was used as the secondary antibody.
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Immunocytochemistry/ Immunofluorescence - MMP17 antibody [EP1270Y]; Immunofluorescent staining of HeLa cells using TA303604 (1:50).
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