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Home Antibody All anti-MMACHC antibodies

Anti-MMACHC TRUEMAB Antibody Clone 1A4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA504954
  • MMACHC mouse monoclonal antibody,clone 1A4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402444) , 20ug Explanation
100ul 325 In Stock
CF504954
  • Carrier-free (BSA/glycerol-free) MMACHC mouse monoclonal antibody,clone 1A4
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(5)
IF(1)
FC(1)
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Also for MMACHC (NM_015506)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human MMACHC(NP_056321) produced in HEK293T cell.
Clone NameClone 1A4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 31.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria (MMACHC)
Alternative NamecblC
Database LinkNP_056321
Entrez Gene 25974 Human
FunctionThe exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMACHC (RC223846, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMACHC.
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504954)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504954)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504954)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504954)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-MMACHC mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504954)
IF Image
Anti-MMACHC mouse monoclonal antibody (TA504954) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMACHC(RC223846).
FC Image
HEK293T cells transfected with either RC223846 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MMACHC antibody(TA504954), and then analyzed by flow cytometry.

 

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