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Home Antibody All anti-MEX3B antibodies

Anti-MEX3B Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320045
  • Rabbit Polyclonal RKHD3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC410265) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenRKHD3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RKHD3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, IF: 20 ug/ml
BufferRKHD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification RKHD3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens mex-3 RNA binding family member B (MEX3B)
Alternative NameMEX-3B; RKHD3; RNF195
Database LinkNP_115622
FunctionRKHD3 Antibody: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Related Pathway

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WB Image
Western blot analysis of RKHD3 in mouse skeletal muscle tissue lysate with RKHD3 antibody at 1 ug/mL.
IF Image
Immunofluorescence of RKHD3 in mouse skeletal muscle cells with RKHD3 antibody at 20 ug/mL.

 

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