Home Antibody All anti-METTL7B antibodies
Also for METTL7B (NM_152637)
|MettL7B antibody was raised against a 16 amino acid peptide near the carboxy terminus of human MettL7B.|
|Human, Mouse, Rat
||WB: 2 - 4 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens methyltransferase like 7B (METTL7B)|
Entrez Gene 196410 Human
Entrez Gene 71664 Mouse
Entrez Gene 366792 Rat
|MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.|
|TransmembraneDruggable Genome |
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Western blot analysis of MettL7B in rat spleen tissue lysate with MettL7B antibody at (A) 2 and (B) 4 ug/ml.
Immunohistochemistry of Mett7LB in human spleen tissue with MettL7B antibody at 2.5 ug/ml.