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Anti-MCRS1 Antibody EPR5855


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against MCRS1
100ul 325 3-7 Days
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Also for MCRS1 (NM_001012300)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MCRS1 was used as an immunogen.
Clone NameEPR5855 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens microspherule protein 1 (MCRS1), transcript variant 2
Alternative NameICP22BP; INO80Q; MCRS2; MSP58; P78
Database LinkNP_001012300
Entrez Gene 10445 Human
Entrez Gene 51812 Mouse
Entrez Gene 300222 Rat
FunctionMCRS1 is a nucleolar protein that contains a bipartite nuclear localization motif, a nucleolar localization motif, a coiled-coil domain, and a forkhead associated domain. Several functions for MCRS1 include a transforming activity, nucleolar sequestration activity, and telomerase inhibition (1). MCRS1 has been associated with a variety of cellular processes, including RNA polymerase I transcription and cell cycle progression (2). Furthermore, MCRS1 can relieve the repressor activity of DAXX, an adaptor protein that links Fas signaling to the c-Jun NH2-terminal kinase pathway via a nucleolar sequestration mechanism (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MCRS1 antibody [EPR5855]; All lanes : Anti-MCRS1 antibody [EPR5855] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HCT 116 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : LnCaP cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 52 kDa.
Assay Image
Other-Anti-MCRS1 antibody [EPR5855](TA310682); Equilibrium disassociation constant (KD)..


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