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Anti-MCRS1 Antibody EPR5855
Also for MCRS1 (NM_001012300)
|A synthetic peptide corresponding to residues in human MCRS1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens microspherule protein 1 (MCRS1), transcript variant 2|
|ICP22BP; INO80Q; MCRS2; MSP58; P78|
|MCRS1 is a nucleolar protein that contains a bipartite nuclear localization motif, a nucleolar localization motif, a coiled-coil domain, and a forkhead associated domain. Several functions for MCRS1 include a transforming activity, nucleolar sequestration activity, and telomerase inhibition (1). MCRS1 has been associated with a variety of cellular processes, including RNA polymerase I transcription and cell cycle progression (2). Furthermore, MCRS1 can relieve the repressor activity of DAXX, an adaptor protein that links Fas signaling to the c-Jun NH2-terminal kinase pathway via a nucleolar sequestration mechanism (1).|
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Western blot - Anti-MCRS1 antibody [EPR5855]; All lanes : Anti-MCRS1 antibody [EPR5855] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HCT 116 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : LnCaP cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 52 kDa.
Other-Anti-MCRS1 antibody [EPR5855](ab124704); Equilibrium disassociation constant (KD)..