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Home Antibody All anti-MCRS1 antibodies

Anti-MCRS1 Antibody EPR5855

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310682
  • Rabbit Monoclonal antibody against MCRS1
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for MCRS1 (NM_001012300)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MCRS1 was used as an immunogen.
Clone NameEPR5855 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens microspherule protein 1 (MCRS1), transcript variant 2
Alternative NameICP22BP; INO80Q; MCRS2; MSP58; P78
Database LinkNP_001012300
Entrez Gene 10445 Human
Entrez Gene 51812 Mouse
Entrez Gene 300222 Rat
FunctionMCRS1 is a nucleolar protein that contains a bipartite nuclear localization motif, a nucleolar localization motif, a coiled-coil domain, and a forkhead associated domain. Several functions for MCRS1 include a transforming activity, nucleolar sequestration activity, and telomerase inhibition (1). MCRS1 has been associated with a variety of cellular processes, including RNA polymerase I transcription and cell cycle progression (2). Furthermore, MCRS1 can relieve the repressor activity of DAXX, an adaptor protein that links Fas signaling to the c-Jun NH2-terminal kinase pathway via a nucleolar sequestration mechanism (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MCRS1 antibody [EPR5855]; All lanes : Anti-MCRS1 antibody [EPR5855] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HCT 116 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : LnCaP cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 52 kDa.
Assay Image
Other-Anti-MCRS1 antibody [EPR5855](TA310682); Equilibrium disassociation constant (KD)..

 

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