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Home Antibody All anti-MCM4 antibodies

Anti-MCM4 Antibody EPR5245

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310681
  • Rabbit Monoclonal antibody against MCM4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416982) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for MCM4 (NM_005914)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human MCM4 was used as an immunogen.
Clone NameEPR5245 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:50000 - 1:200000; IP: 1:10 - 1:100; FC: 1:100 - 1:500
BufferDoes not react with Rat. Is unsuitable for ICC/IF or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens minichromosome maintenance complex component 4 (MCM4), transcript variant 1
Alternative NameCDC21; CDC54; hCdc21; NKCD; NKGCD; P1-CDC21
Database LinkNP_005905
Entrez Gene 4173 Human
Entrez Gene 17217 Mouse
FunctionMCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of MCM4 by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex (1).
Related PathwayStem cell - PluripotencyTranscription Factors DNA replicationCell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MCM4 antibody [EPR5245]; All lanes : Anti-MCM4 antibody [EPR5245] at 1/50000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Molt-4 cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 97 kDa.
Assay Image
Other-Anti-MCM4 antibody [EPR5245](TA310681); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-MCM4 antibody [EPR5245]; Flow cytometric analysis of permeabilized Molt-4 cells using anti-MCM4 in red or a rabbit IgG in green(negative).

 

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