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Home Antibody All anti-MCM3 antibodies

Anti-MCM3 Antibody EPR7081

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310680
  • Rabbit Monoclonal antibody against MCM3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419355) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human MCM3 was used as an immunogen.
Clone NameEPR7081 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens minichromosome maintenance complex component 3 (MCM3), transcript variant 2
Alternative NameHCC5; P1-MCM3; P1.h; RLFB
Database LinkNP_001257401
Entrez Gene 4172 Human
FunctionMCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and the recruitment of other DNA replication related proteins. MCM3 is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. MCM3 also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression (1).
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome DNA replicationCell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-MCM3 antibody [EPR7081]; All lanes : Anti-MCM3 antibody [EPR7081] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : K562 cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 91 kDa.
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Other-Anti-MCM3 antibody [EPR7081](TA310680); Equilibrium disassociation constant (KD)..
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Flow Cytometry - Anti-MCM3 antibody [EPR7081]; TA310680, at 1/10 dilution staining MCM3 in permeabilized 293T cells by Flow Cytometry (red). A rabbit IgG negative control is shown in green.
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