Home Antibody All anti-MCM3 antibodies
Also for MCM3 (NM_002388)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 42 and 272 of MCM3|
|WB, IHC, IF
||WB:1:5000-1:20000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens minichromosome maintenance complex component 3 (MCM3), transcript variant 1|
|HCC5; P1-MCM3; P1.h; RLFB|
|The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HepG2 (anti-MCM3 antibody diluted at 1:10000)
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using MCM3(anti-MCM3 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MCM3(anti-MCM3 antibody) antibody at 1:500 dilution.