Home Antibody All anti-MCM3 antibodies
Also for MCM3 (NM_002388)
|Recombinant fragment corresponding to a region within amino acids 42 and 302 of MCM3 (Uniprot ID#P25205)|
|Human (Predicted: Rhesus Monkey)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rhesus Monkey (100%)
|Homo sapiens minichromosome maintenance complex component 3 (MCM3), transcript variant 1|
|HCC5; P1-MCM3; P1.h; RLFB|
Entrez Gene 4172 Human
Entrez Gene 708320 Monkey
|The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]|
|Stem cell - PluripotencyTranscription FactorsDruggable Genome DNA replicationCell cycle|
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Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308761 diluted at 1:10000.
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using MCM3(TA308761) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MCM3(TA308761) antibody at 1:500 dilution.