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Home Antibody All anti-MCL1 antibodies

Anti-MCL1 TRUEMAB Antibody Clone 10D10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500990
  • anti-MCL1 mouse monoclonal antibody, clone 10D10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411855) , 20ug
100ul 325 In Stock
CF500990
  • Carrier-free (BSA/glycerol-free) MCL1 mouse monoclonal antibody, clone 10D10
100ug $450 3-4 weeks
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WB(1)
IHC(2)
IF(1)
FC(1)
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Also for MCL1 (NM_021960)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human MCL1 (NP_068779) produced in HEK293T cell.
Clone NameClone 10D10 IsotypeIgG2a
Species ReactivityHuman Concentration0.95mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens myeloid cell leukemia 1 (MCL1), transcript variant 1
Alternative Namebcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
Database LinkNP_068779
FunctionThe protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Related Pathway
Apoptosis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCL1 (RC200521, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MCL1.
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-MCL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500990, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-MCL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500990, Dilution 1:50)
IF Image
Anti-MCL1 mouse monoclonal antibody (TA500990) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MCL1(RC200521).
FC Image
HEK293T cells transfected with either pCMV6-ENTRY MCL1(RC200521)(Red) or empty vector control plasmid(Blue) were immunostained with anti-MCL1 mouse monoclonal(TA500990), and then analyzed by flow cytometry.

 

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