Home Antibody All anti-MBD4 antibodies
Also for MBD4 (NM_003925)
|Synthetic peptide surrounding amino acid 474 of mouse MBD4|
|Human, mouse, rat
|100 µg (0.5 mg/ml) affinity purified rabbit anti-MBD4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Homo sapiens methyl-CpG binding domain protein 4 (MBD4), transcript variant 1|
Entrez Gene 8930 Human
Entrez Gene 17193 Mouse
Entrez Gene 680915 Rat
|MBD4 (methyl-CpG-binding domain protein 4) belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2, MBD1, MBD2, and MBD4, except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis.|
|Druggable Genome Base excision repair|
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Western blot analysis of MBD4 using Jurkat cell lysate.