Home Antibody All anti-MATN2 antibodies
Also for MATN2 (NM_002380)
|MATN2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human MATN2.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens matrilin 2 (MATN2), transcript variant 1|
Entrez Gene 4147 Human
Entrez Gene 17181 Mouse
Entrez Gene 299996 Rat
|Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.|
|Secreted Protein |
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Western blot analysis of MATN2 in human liver tissue lysate with MATN2 antibody at (A) 1 and (B) 2 µg/ml.