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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-MAT2A antibodies

Anti-MAT2A Antibody

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SKU Description Amount Price Availability*  
TA301493
  • Rabbit Polyclonal Antibody against MAT2 alpha
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401791) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(2)
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Also for MAT2A (NM_005911)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens methionine adenosyltransferase II, alpha (MAT2A)
Synonyms:MATA2; MATII; SAMS2
ImmunogenSynthetic peptide made to an N terminal portion of the human protein (within residues 1-100). [Swiss-Prot# P31153]
BufferPBS, 30% glycerol and 0.1% sodium azide
Clone Name Isotype
Species ReactivityHuman, Rat, Orangutan, Bovine, Zebrafish, Monkey; not mouse Concentration1.35 mg/ml
Purification peptide affinity purified (Protein A or G Sepharose)
Guaranteed Application *WB Suggested DilutionsWB: 1.0 ug/ml
BackgroundMAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.
Related Pathway

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HEK293T cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY MAT2A (RC200926) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAT2A.
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Detection of MAT2A in HepG2 whole cell lysates

 

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